Structura Biotechnology

Structura Biotechnology Inc. is a Toronto-based biotechnology startup founded in 2016 and affiliated with the University of Toronto. The company focuses on developing machine learning algorithms and software solutions to enhance structural biology research and drug discovery.

Their flagship product, CryoSPARC, is a software platform that utilizes GPU-powered machine learning to analyze cryo-electron microscopy (cryo-EM) data. CryoSPARC enables rapid 3D reconstruction of protein molecules and offers features such as real-time data analysis, high-resolution refinement, and solutions for single-particle cryo-EM analysis. This technology supports research on membrane proteins, ion channels, GPCRs, and drug targets, and has been instrumental in solving critical protein structures, including the SARS-CoV-2 spike protein.

Structura has partnered with Thermo Fisher Scientific to integrate their software with advanced cryo-TEM technology, enhancing real-time data analysis capabilities. The company operates with a small team and has been recognized in the NVIDIA Inception accelerator program for its contributions to AI and data sciences.