Centerline Biomedical

About

Centerline Biomedical, Inc. is a biomedical company based in Cleveland, Ohio, founded in 2014 as a spinoff from the Cleveland Clinic. The company specializes in radiation-free 3D visualization and real-time navigation technology for endovascular procedures. Its flagship product, the Intra-Operative Positioning System (IOPS®), is an FDA-cleared platform that provides non-x-ray-based 3D guidance for vascular interventions, particularly in the descending aorta. The IOPS system creates detailed 3D maps of vascular anatomy from existing images and utilizes electromagnetic tracking for real-time guidance. This technology enhances surgical precision, reduces procedure times, and minimizes reliance on harmful X-ray fluoroscopy. Centerline's mission focuses on improving patient safety and outcomes by providing advanced navigation tools that support minimally invasive procedures. The company has been recognized with a 2024 MedTech Outlook Award for its contributions to surgical devices and has been adopted by leading vascular centers, including the Cleveland Clinic.